Rat model of cardiopulmonary bypass for deep hypothermic circulatory arrest
نویسندگان
چکیده
منابع مشابه
Deep hypothermic circulatory arrest.
Effective cerebral protection remains the principle concern during aortic arch surgery. Hypothermic circulatory arrest (HCA) is entrenched as the primary neuroprotection mechanism since the 70s, as it slows injury-inducing pathways by limiting cerebral metabolism. However, increases in HCA duration has been associated with poorer neurological outcomes, necessitating the adjunctive use of antegr...
متن کاملCurrent status of antifibrinolytics in cardiopulmonary bypass and elective deep hypothermic circulatory arrest.
Cardiopulmonary bypass (CPB) results in many physiologic derangements, including activation of the hemostatic and fibrinolytic pathways. Deep hypothermic circulatory arrest (DHCA) adds a further insult to the coagulation systems because it involves more extreme hypothermia and organ ischemia related to blood stasis. The abnormalities induced by CPB disrupt the checks and balances in the hemosta...
متن کاملPerioperative management of deep hypothermic circulatory arrest.
m d t r e t n a a h c n i l r t 1 t d u t 2 g g l t HE GOAL OF this article is to provide a review of deep hypothermic circulatory arrest (DHCA), covering major isues including pathophysiology of ischemic injury, organ protecion (both pharmacologic and nonpharmacologic), temperature ontrol, and perfusion methods. The purpose of this review is to erve as a resource for board review or as introdu...
متن کاملCardiopulmonary bypass with deep hypothermic circulatory arrest for a patient with sickle cell anemia: a case report.
A 36-year-old sickle cell anemia patient undergoing a pulmonary thromboendarterectomy required the use of cardiopulmonary bypass incorporating deep hypothermic circulatory arrest. Being aware of reported incidences of sickling crises, a team of the surgeon, anesthesiologist, hematologist, and perfusionist met to devise a plan of treatment. Treatment included preoperative and intraoperative exch...
متن کاملPlasma cefazolin levels during cardiovascular surgery: effects of cardiopulmonary bypass and profound hypothermic circulatory arrest.
OBJECTIVES We sought to assess the effects of cardiopulmonary bypass and profound hypothermic circulatory arrest on plasma cefazolin levels administered for antimicrobial prophylaxis in cardiovascular surgery. METHODS Four groups (10 patients per group) were prospectively studied: vascular surgery without cardiopulmonary bypass (group A), cardiac surgery with a cardiopulmonary bypass time of ...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 2011
ISSN: 0022-5223
DOI: 10.1016/j.jtcvs.2011.01.062